The ASL 5000® is the world’s most sophisticated breathing simulator, and capable of simulating the full range of patients  – neonatal to adult. The ASL 5000® is able to breathe spontaneously even while being ventilated and can be used with any ventilator (and any ventilator mode). The ASL 5000® can help you save time, accelerate development and gain better control of testing protocols.

Intended Use

This highly accurate, versatile instrument represents the premier choice for product development and testing for ventilators, CPAP, aerosol drug delivery and other respiratory therapy devices. Review this list of research studies using the ASL 5000® to learn about how others are using the ASL 5000®.

Are You an Educator?

Engineers and researchers – read on!

Use the ASL 5000® to:

  • Perform long term testing on all ventilator modes with virtually any patient type
  • Develop adaptive algorithms on ventilators
  • Simulate patient breathing associated with sleep apnea for development of CPAP devices
  • Evaluate aerosol drug delivery devices using realistic high-flow inhalation
  • Compare ventilators or ventilator modes (e.g. pressure support mode) on the same reproducible patient
  • Create repeatable breath patterns at a high level of accuracy for respiratory device product development with the smart pump

Automated Control

Data Analysis

  • 100+ parameters for detailed analysis of entire patient breath cycle
  • Export all data including waveforms and breath parameters for deeper statistical analysis
  • 512 Hz sampling rate provides very granular feedback across a wide range of breath rates


  • Highly accurate throughout the entire range of neonatal to adult tidal volumes and breath rates
  • Calibrated system traceable to NIST standards (sample calibration certificate)
  • Flow calculated from piston position eliminates the uncertainties of external flow meters.
Photos & Videos

Simulator Bypass and Leak Valve Module (SBLVM)

Sets three levels of leaks. Also switches between ASL 5000® and external breathing bag when no simulation is running to avoid ventilator alarms. Learn more.

Fast Oxygen Module (FOM)

Delivers reading almost instantaneously from a highly accurate paramagnetic oxygen sensor.

Cylinder Temperature Controller (CTC)

Set the wall temperature of the ASL 5000® to manage humidified patient circuits.

Analog I/O Option

Analog input – 2 channels, 0-10V single-ended or differential input with scalable software gain and offset to control real-time lung parameters

Analog output – 2 channels, -10V to 10V with scalable output range and offset for various real-time lung parameters

Auxiliary Gas Exchange Cylinder (AGEC)

Bag-in-bottle accessory for use of ASL 5000® with aerosol drugs and anesthesia gases. Learn more.

PreemieLung™ Option

Add-on cylinder for the ASL 5000® Breathing Simulator for specialized applications requiring increased accuracy in the neonatal range. Learn more.

ASL 5000® XL

Larger cylinder extends total volume from 2 ml to 5.4 L
(max 5.4 L tidal volume).

Carrying Case

Hard shell case protects the device during shipping and air transport.

Tidal volumesStandard ASL: 2 mL - 2.5 L
ASL 5000 XL: 2 mL - 5.4 L
Volume uncertainty ranges:
up to 10 mL greater of ± 10% of reading or 1mL
up to 100 mL greater of ± 2.5% of reading or 2.5 mL
up to 1000 mL greater of ± 2% of reading or 20 mL
Functional Residual Capacity (FRC)100 – 1500 mL
Spontaneous breathing capabilitiesMuscle pressure: 0 - 50 cmH2O typical range (max achievable range 0 - 100 cmH2O) (0 = Passive/ Apneic Patient)
Breath rate: 3 - 150 bpm
Peak flow270 L/min ± 10% (t90Flow < 50 ms)
Flow accuracy: +/- 2% of reading
Resistance settings3 - 500 cmH₂O/L/s (linear and parabolic resistor types)
Resistance accuracy +/- 10% of reading
Compliance settings0.5 - 250 mL/cmH₂O
Compliance accuracy: +/- 5% of reading
Small signalgreater than 15 Hz bandwidth (10mL response - HF ventilation)
Airway pressureaccuracy +/- 1% fso measurement
Barometric pressureaccuracy +/- 1% (1kPa)
Gas temperatureaccuracy +/- 0.5 degrees C (20 – 45 degrees C)
Digital OutputDigital output – 5V TTL signals for inspiration/expiration, 50 ms trigger pulse at beginning of patient effort
Motion controlHigh frequency (2 kHz) digital servo system and state-of-the-art brushless motor drive for smooth response to ventilator transients
DimensionsStandard ASL 5000: 8.6 x 16.8 x 12.4 inches (219 x 425 x 315 mm)
Weight22 lbs (10 kg)

The ASL 5000® Breathing Simulator gives you the ventilator-grade lungs you need for testing and training.

What types of patients can I simulate?

The ASL 5000® can simulate neonatal through adult patients with COPD, ARDS, pneumothorax, fibrosis, or most other diseases affecting pulmonary dynamics.

Can I use the ASL 5000 on any ventilator?

Yes, the ASL 5000® can be used with ANY ventilator.  The ASL has a standard 22mm tapered port that connects to all ventilator circuits.  Enhance the realism with the RespiPatient® manikin to include an ET-tube, LMA or mask (for non-invasive ventilation).

Will all ventilators work the same way with the ASL 5000?

No, they will not. Ventilatory results may vary between ventilators, even when using identical settings. The ASL 5000® is a valuable tool for uncovering these ventilator performance variances and characteristics. Read about research by Gerald Moody (Children’s Medical Center in Dallas) on two subacute/homecare ventilators: Differences in Ventilator Performance Characteristics and Patient Response. 

Can my ASL 5000® be used with my manikin?

The ASL 5000® is compatible with the Laerdal SimMan 3G series manikins. The ASL 5000® is managed directly from Laerdal’s acclaimed LLEAP platform so there is no need to learn new software. We also offer our own RespiPatient® manikin with over thirty curriculum modules for ventilator management training. Technically speaking, these two models are the only truly compatible manikins. However, some organizations do manage to configure their own “non-compatible” manikins to function with the ASL 5000®.

How does the ASL 5000 interface with a ventilator?

The ASL 5000® can be connected to the ventilator using any standard tubing or breathing circuits via a 22mm ISO port on the front of the instrument. Or, if using a manikin, you would intubate the manikin and connect the ventilator to the ET Tube, just like a real patient.

Is the ASL 5000 Software compatible with Windows 7?

The current software version (3.6) is compatible with Windows 7, Windows 8.1 and Windows 10.

Is the ASL 5000 Software compatible with the Apple Mac OS?

While there is no native Mac OS support, the software can be used through a virtual machine (e.g. Parallels or VMWare Fusion) running Windows 7, Windows 8.1 or Windows 10.

What are the computer requirements for running the ASL 5000?

To ensure a smooth startup, a laptop computer with ASL 5000® software installed is provided in the standard package. If other PCs are used, we recommend the following: a 500 GB HD, 4 GB RAM, i5 processor Windows 10 is the recommended operating system. Windows 7 is compatible. Windows 8 is not recommended. The screen should have a size of at least 15” and a minimum resolution, based on screen aspect ratio: 4:3 – At least 1280 x 960 16:9 – At least 1600 x 900 16:10 – At least 1440 x 900 1080p resolution is recommended.

Which models can I upgrade to the latest software/firmware combination (3.6)?

ASL 5000® devices with a serial number greater than 0800 may be upgraded to the latest software and firmware release. Older devices may be upgraded after a required hardware update. Please contact Customer Care for further information (

Can I use the ASL 5000 with aerosol agents?

Yes. The IngMar Medical Auxiliary Gas Exchange Cylinder (AGEC) for the ASL 5000® is required for aerosol usage. The AGEC consists of a clear acrylic cylinder with openings at the top and bottom, allowing it to act as a “bag-in-bottle” device. This will serve to protect the ASL’s cylinder from any incompatible substances.

Can I use the ASL 5000 with humidified air?

Yes, but the ASL 5000® requires the Cylinder Temperature Controller (CTC) Option for use with humidified air. With the CTC, the ASL 5000® cylinder will be heated up to between 37-40℃ to ensure that condensation and bacterial growth are prevented.

Do I need to calibrate the ASL 5000?

For research or engineering purposes, we would strongly recommend annual calibration. After 12 months the pressure transducer error can be expected to exceed the specified limits (1% full scale) for <20% of the instruments. Therefore, if you are using the device for applications in a controlled metrology environment, you may want to consider re-calibration after six months. Within 6 months the pressure transducer drift can be expected to be within the specified limits for all instruments.

For educational usage, we would recommend calibration once every two years.

What is the volume resolution of the ASL 5000®?

The standard ASL 5000® has a volume resolution of 12.4 µL based on a 4mm ball screw pitch.  The ASL 5000® XL has a volume resolution of 16.2 µL based on a 4mm ball screw pitch.

Can the ASL 5000 simulate leaks realistically?

You can simulate ET Tube leaks, circuit leaks, mask leaks, etc. by using the RespiPatient® manikin or by attaching another manikin or intubation head. If you aren’t concerned about applying a mask and just want to cover the basics of NIV settings, you can attach the tubing directly from the NIV machine to the front of the ASL 5000®. You then select a leak level using the optional Simulator Bypass and Leak Valve Module (SBLVM). The ASL 5000® is also capable of simulating a leak in the patient’s lungs.

Can the ASL 5000 simulate the effects of Jet Ventilation?

Yes, the tubing which would normally connect to the patient would simply be connected to the ASL 5000® instead. These scenarios would typically require neonates with very small tidal volumes, high respiratory rate, and decreased compliance, and the ASL 5000® is the only simulator capable of representing this type of patient. The tidal volume range for the ASL 5000® is 2 mL to 2.7 L, and the compliance range is 0.5 mL/cmH2O to 250 mL/cmH2O. For this application, you may want to consider the PreemieLung Option.

Quality Management and ISO Standards

  • IngMar Medical is ISO 9001:2015 Certified (Registration Nr. 74 300 3727).
  • Our calibration lab is accredited to ISO/IES 17025:2017 (Certificate Nr. 4172.01)
  • The ASL 5000 meets or exceeds the requirements for test lungs used for volume testing as specified in the following standards:
    • ISO 80601-2-12:2011 (Critical Care Ventilators)
    • ISO 80601-2-13:2011 (Anesthetic Workstations)
    • ISO 10651-6:2004 (Home Care Ventilatory Support Devices)
    • ISO 10651-3:1997 (Emergency and Transport Ventilators)

Also Consider

  • QuickLung® Precision Test Lung with adjustable resistance and compliance. Learn more.
  • QuickLung® Breather with five spontaneous breath patterns. Learn more.

Research Studies

For an extensive list of published research studies using the ASL 5000® click here.


  • Measurement Uncertainty and Advanced Verification of the ASL 5000®. Watch.
  • Automated Device Testing with the TAI Watch.
  • Troubleshooting 101 Watch.