More Realistic Aerosol Device Testing

Bring your in vitro respiratory drug delivery testing closer to real life with the ASL 5000™ Breathing Simulator. The ASL 5000™ Breathing Simulator can dynamically render models that include high-fidelity respiratory mechanics and patient effort, from neonatal to adult. More than just a flow pump, the ASL 5000 enables you to shape your flow curves to generate realistic breathing profiles (flow vs. time) that can be employed to test metered dose inhalers (MDIs), dry powder inhalers (DPIs), nebulizers, spacers, and valved holding chambers.

Use the ASL 5000 to:

Test all types of drug delivery devices including nebulizers, inhalers (MDIs and DPIs), and spacers

Simulate One Breath at a Time

  • Precisely define and apply breathing profiles for patients of all sizes with the ASL 5000 XL (2 mL to 6 L tidal volume range).
  • Vary tidal volumes, I:E-ratios, and breath-holds.

Analysis and Validation

  • All data files can be exported as human readable text files that can easily be imported into programs like Excel for further data analysis.
  • Validate performance to international standards and pharmacopeia.


  • Interface with particle size analyzers (next generation impactors) to apply breathing patterns and precise triggering.
  • Conduct experiments while protecting the ASL 5000 from contamination by emitted drugs with the Auxiliary Gas Exchange Cylinder (AGEC)
    Learn more