Download the latest installer for RespiSim® Software 4.0 as well as all current product documentation below.


RespiSim Software 4.0 Installer (version 4.0.20428.1)

  • Please note: Windows 10 is required.
  • Current ASL 5000/ RespiSim users:  A purchased license is required to connect your ASL 5000 with the RespiSim 4.0 Software. Please contact to inquire about our 60-day free trial as well as purchasing a permanent license.
  • Current RespiSim Software 4.0 users:  Please exit the RespiSim Software and reboot your system before upgrading to the latest version.
  • Before running the RespiSim installer, please download and install any available Windows updates, and restart your computer.
  • Administrator access is required to install and to operate. Windows User Account Control must be enabled in the User Account control panel. A setting of “Never Notify” will disable User Account Control access, and is therefore incompatible with RespiSim software. Please ask an Administrator to re-enable User Account Control if you are not seeing the User Account Control prompt upon installing or launching RespiSim.
  • For assistance, please contact Client Success at or (412) 441-8228, Option 1.

RespiSim Scenarios
Intended for any RespiSim Software 4.0 user. Includes description and download for each RespiSim Scenario included with purchase.

RespiSim User Manual
Intended for any new RespiSim Essential or RespiPro™ user. Includes detailed instruction on how to use RespiSim Software and associated hardware.

RespiSim Software Quick Setup Guide
Intended for any new RespiSim Essential or RespiPro user OR any ASL 5000™ Breathing Simulator user who has upgraded to RespiSim 4.0 Software. Includes steps to:
1. Download and install the RespiSim Software
2. Activate your RespiSim Software license
3. Connect to the ASL 5000 Breathing Simulator
4. Connect to the Patient Monitor Application on the Learner Display

RespiSim Learner Display Hardware Quick Setup Guide
Intended for all existing ASL 5000/ RespiSim users who have upgraded to RespiSim 4.0 Software. Includes steps to set up and assemble the Learner Display hardware to use either free-standing or mounted to a legacy ASL 5000/ RespiPatient mobile cart.

RespiPro Hardware Quick Setup Guide
Intended for users of the RespiPro. This guide includes steps to:
1. Remove the RespiPro from the shipping crate
2. Assemble and mount the Instructor Display
3. Assemble and mount the Learner Display

RespiSim Validated Lung Models –  Parameters

RespiSim Validated Lung Models – References

Release Notes (version 4.0.20428.1)

What’s improved/enhanced from prior version (4.0.10722)?

  • Updates to breath detection parameters to allow more accurate detection of small breaths on neonatal models

  • Erroneous multiple breaths are no longer detected

  • Improved synching of displayed waveforms in the UI

  • Live waveform data is now filtered to remove sporadic spikes due to noise

  • Added additional error handling and logging around ASL 5000 connection logic

  • Improved connectivity of RespiScope devices to now support multiple connection attempts per session

  • Updated RespiScope playlist format for newer RespiScope firmware versions

  • Fixed issues related to RespiScope data export and import

  • Upgraded to .NET 5 from .NET Core 3.1 for added stability and future-proofing

Known bugs to be addressed in the next release:

  • When running RespiSim Software with a non-intubated RespiPro Manikin, some adult lung models cause severe oscillations (generally lung models with low airway resistance). This issue has been documented with the following lung models:  Normal High Effort (Adult) and Emphysema (Adult). These lung models will oscillate enough to impact performance. Please note there is some minor waveform oscillation in the software before a breath is triggered with some lung models, but this oscillation does not hinder performance.
  • When running RespiSim Software with an intubated RespiPro Manikin, some adult lung models in an apneic state will cause the RespiSim Software Live Data to fluctuate or read incorrectly. The waveforms in the RespiSim Software display correctly and the ventilator performance is not impacted. This error is also dependent on ventilator settings. We have noted that using settings with higher pressures seems to improve the Live Data readings.

  • When running RespiSim Software with a spontaneously breathing manikin, the Live Data PIP reading will generally be lower than what is being delivered by the ventilator.

  • Note that the tubing connecting the ASL 5000 to the RespiPro Manikin should not be shortened or exchanged for different tubing.

Coming Soon

  • Improved connectivity with the Patient Monitor
  • Ability to use a shortned tubing set-up from the ASL 5000 to the RespiPro Manikin