In a recent study by Robert Chatburn and Steven Zhou, the ASL 5000 Breathing Simulator was used to create a patient diagnosed with COPD and a normal patient devoid of ailments limiting pulmonary function.¹ The lung model parameters (e.g. resistance, compliance, patient effort profile) were derived from previously published studies.
To create the COPD patient model using the ASL 5000, enter the following parameters within the Choose a Lung Model step:
For further instruction on enabling Rin v. Rout, refer to our last Tips & Tricks entry, Setting Independent Inspiratory and Expiratory Resistances.
Enter the remaining parameters within the Choose a Patient Effort Model step:
Note, both patients (COPD and normal) achieved the same tidal volume value (685 mL). In order to demonstrate this, the muscle pressure (Pmax) was increased from 11.95 cmH20 to 24.52 cmH20. This was necessary to overcome the diseased lung characteristics (Rin, Rout, and C) of the COPD patient.
¹Chatburn RL, Zhou S. Effect of the anatomic reservoir on low-flow oxygen delivery via nasal cannula: constant flow versus pulse flow with portable oxygen concentrator. Respir Care 2014;59(8):1*. To access the study click here.